Clinical Hemp OilsTM
Extraordinary hemp therapeutics reuniting science and Nature.
Our mission is serving your health practice.
Cannacea offers practitioners scientific hemp oil supplements with certified clinical constituency and purity. Through years of research and development, Cannacea was founded to craft the ultimate phytocannabinoid therapeutics. Today, Cannacea excels for your patients’ health.
The Endocannabinoid System (ECS) is involved in multiple physiological and psychological functions of clinical interest. Notably, the ECS and the functions it regulates can be variably modulated by phytocannabinoids. [1-3]
Clinical studies indicate the intake of phytocannabinoids can provide health benefits for some people [4-8, 14, 15, 21, 22]. The efficacy and safety of phytocannabinoid intake appears to improve when delivered in a full spectrum complex instead of in isolation [see subsection].
Clinical applications demand endocannabinoid supplements be science-driven phytocannabinoid preparations with exceptional certified potencies and purity. 
CANNACEA – Clinical Phytochemistry and Purity.
- Formulations based on advanced research, analytics, and development.
- Lab-certified complete hemp trichome phytochemistry for effective endocannabinoid supplementation.
- Rigorously-validated certified organic ingredients, processing, and manufacture in a cGMP Certified facility (BRCGS).
- Leading quality assurance, transparency, and safety for clinical applications:
Click on the section headings below to discover the science and special qualities of Cannacea hemp oils.
Or directly action one of the following:
MACADAMIA NUT OIL
Organic Macadamia Nut Oil Excipient
We harness a legendary therapeutic oil and use cold-pressed organic Macadamia Nut Oil as excipient. With its exquisite aroma and flavor, it also gives our hemp oils superb absorbability and stability, while keeping them primarily fluid if refrigerated.
Macadamia Nut Oil also provides one of Nature’s optimal fatty acid profiles dominated by monounsaturates:
- Oleic Acid – C18:1 Omega-9 MUFA (> 50%)
Famous MUFA that is likewise the primary fatty acid in olive oil.
- Palmitoleic Acid – C16:1 Omega-7 MUFA (> 15%)
Rare in most plant oils , this MUFA is prevalent in macadamia nuts and in human fatty tissues .
The primary fatty acids in Cannacea oils are the primary fatty acids in human depot fat (oleic, palmitic, palmitoleic, linoleic, stearic & myristic acids) [CoAs, 11]. We’re studying if that’s why our formulations provide significantly enhanced absorbability compared with typical oils [IP].
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- Stasiulewicz, A et al. (2020). A Guide to Targeting the Endocannabinoid System in Drug Design. International Journal of Molecular Sciences 21(8): 2778.
- VanDolah, HJ et al. (2019). Clinician’s Guide to Cannabidiol and Hemp Oils. Mayo Clinic Proceedings 94(9): 1840-1851.
- Sholler, DJ et al. (2020). Therapeutic Efficacy of Cannabidiol (CBD): A Review of the Evidence from Clinical Trials and Human Laboratory Studies. Current Addiction Reports 7(3): 405-412.
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- National Academies of Sciences, Engineering, and Medicine (2017). The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendations for Research. Washington, DC: The National Academies Press.
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- Orsavova, J et al. (2015). Fatty Acids Composition of Vegetable Oils and Its Contribution to Dietary Energy Intake and Dependence of Cardiovascular Mortality on Dietary Intake of Fatty Acids. International Journal of Molecular Sciences 16(6): 12871-12890.
- Krut, LH, Bronte-Stewart, B (1964). The fatty acids of human depot fat. Journal of Lipid Research 5(3): 343-351.
- Turner, SE et al. (2017). Molecular Pharmacology of Phytocannabinoids. In Kinghorn, AD; Falk, H; Gibbons, S; Kobayashi, J (eds.). Phytocannabinoids: Unraveling the Complex Chemistry and Pharmacology of Cannabis sativa. Progress in the Chemistry of Organic Natural Products 103. Springer International Publishing: 61–101.
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- Capano, A et al. (2020). Evaluation of the effects of CBD hemp extract on opioid use and quality of life indicators in chronic pain patients: a prospective cohort study. Postgraduate Medicine 132(1): 56-61.
- Casarett, DJ et al. (2019). Benefit of Tetrahydrocannabinol versus Cannabidiol for Common Palliative Care Symptoms. Journal of Palliative Medicine 22(10): 1180-1184.
- Wagner, H, Ulrich-Merzenich, G (2009). Synergy research: Approaching a new generation of phytopharmaceuticals. Phytomedicine 16(2-3): 97-110.
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- McPartland, JM, Russo, EB (2001). Cannabis and Cannabis Extracts: Greater Than the Sum of Their Parts? Journal of Cannabis Therapeutics 1(3-4): 103-132.
- Russo, E (2011). Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. British Journal of Pharmacology 163(7): 1344-1364.
- Pamplona, FA et al. (2018). Potential Clinical Benefits of CBD-Rich Cannabis Extracts Over Purified CBD in Treatment-Resistant Epilepsy: Observational Data Meta-analysis. Frontiers in Neurology 9: 759.
- Zafar, R et al. (2021). Medical cannabis for severe treatment resistant epilepsy in children: a case-series of 10 patients. BMJ Paediatrics Open 5: e001234.
- Gallily, R et al. (2015). Overcoming the Bell-Shaped Dose-Response of Cannabidiol by Using Cannabis Extract Enriched in Cannabidiol. Pharmacology and Pharmacy 6: 75-78.
- Lewis, MA et al. (2018). Pharmacological Foundations of Cannabis Chemovars. Planta Medica 84(04): 225-233.
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